IP₃ 3-kinase B prevents bone marrow failure

Networking in metabolism and human disease

MEL-18, a tumor suppressor for aggressive breast cancer

IER3 in pancreatic carcinogenesis

Sexual selection and cancer biology

Radiation holidays stimulate tumor immunity

Ubiquitin signals the demise of AMPA receptors

KLF 6: a mitochondrial regulator in the kidney

Unleashing rapamycin in fibrosis

Angiogenesis and bleeding disorders in FNAIT

Holding it together: Naa60 at the Golgi

Astrocytic TGF-β1: detrimental factor in ALS

Healed by our inner fish?

SUMO in the DNA damage response

Gatekeepers of pancreas: TEAD and YAP

GWAS reveal novel IgA nephropathy risk loci

Bidirectional talk between AhR and Oct4

Vimentin gets a new glow from zinc

N⁶-methyladenine: a potential epigenetic mark in eukaryotes

A nuclear sensor of mitochondrial function

Plant immune receptor decoy: Pathogens in their own trap

Oncogenic cancer/testis antigens: prime candidates for immunotherapy

p53 and rapamycin are additive

A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells

TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney

p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion

Hypermaintenance and hypofunction of aged spermatogonia: insight from age-related increase of Plzf expression

The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

Macrolide analog F806 suppresses esophageal squamous cell carcinoma (ESCC) by blocking β1 integrin activation

Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion

Vimentin contributes to epithelial-mesenchymal transition cancer cell mechanics by mediating cytoskeletal organization and focal adhesion maturation

Radiation-induced microRNA-622 causes radioresistance in colorectal cancer cells by down-regulating Rb

miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma

Deficiency of caspase 3 in tumor xenograft impairs therapeutic effect of measles virus Edmoston strain

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cells

MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1

Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients

Ca²⁺/calmodulin-dependent protein kinase IIγ enhances stem-like traits and tumorigenicity of lung cancer cells

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Orosomucoid 2 inhibits tumor metastasis and is upregulated by CCAAT/enhancer binding protein β in hepatocellular carcinomas

Leptin signaling enhances cell invasion and promotes the metastasis of human pancreatic cancer via increasing MMP-13 production

Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome

Recombinant human alpha fetoprotein synergistically potentiates the anti-cancer effects of 1’-S-1’-acetoxychavicol acetate when used as a complex against human tumours harbouring AFP-receptors

Intelectin 1 suppresses tumor progression and is associated with improved survival in gastric cancer

Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells

Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor

MET expression and copy number heterogeneity in nonsquamous non-small cell lung cancer (nsNSCLC)

miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A

ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer

Hepatoma-derived growth factor/nucleolin axis as a novel oncogenic pathway in liver carcinogenesis

Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity

Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4

Vitamin D₃-dependent VDR signaling delays ron-mediated breast tumorigenesis through suppression of β-catenin activity

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion

Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells

Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling

PBRM1 suppresses bladder cancer by cyclin B1 induced cell cycle arrest

Polyphenol-rich extract of Pimenta dioica berries (Allspice) kills breast cancer cells by autophagy and delays growth of triple negative breast cancer in athymic mice

Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer

Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling

Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer

SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: whole-genome analysis in patients with hepatocellular carcinoma

By recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer

Neutrophils trigger a NF-κB dependent polarization of tumor-supportive stromal cells in germinal center B-cell lymphomas

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells

Nuclear EGFR impairs ASPP2-p53 complex-induced apoptosis by inducing SOS1 expression in hepatocellular carcinoma

Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies

A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia

ATRX represses alternative lengthening of telomeres

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)

Deguelin inhibits vasculogenic function of endothelial progenitor cells in tumor progression and metastasis via suppression of focal adhesion

¹¹¹In-cetuximab as a diagnostic agent by accessible epidermal growth factor (EGF) receptor targeting in human metastatic colorectal carcinoma

ERG deregulation induces IGF-1R expression in prostate cancer cells and affects sensitivity to anti-IGF-1R agents

Mcl-1 is an important therapeutic target for oral squamous cell carcinomas

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer

TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma

Longitudinal study on circulating miRNAs in patients after lung cancer resection

Difference between observed and expected number of involved lymph nodes reflects the metastatic potential of breast cancer independent to intrinsic subtype

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma

Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: Implications for targeted EZH2 inhibitor therapy?

Evaluation on efficacy and safety of tyrosine kinase inhibitors plus radiotherapy in NSCLC patients with brain metastases

Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort

Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer

Six stroma-based RNA markers diagnostic for prostate cancer in European-Americans validated at the RNA and protein levels in patients in China

Distinctive clinical characteristics of malignant mesothelioma in young patients

High-throughput RNAi screening of human kinases identifies predictors of clinical outcome in colorectal cancer patients treated with oxaliplatin