Role of seizure in neonatal stroke

Amyloid-β breaks brain’s neuroprotection

ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5

Endogenous IL-33 has no effect on the progression of fibrosis during experimental steatohepatitis

Aging-dependent DNA hypermethylation and gene expression of GSTM1 involved in T cell differentiation

Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection

Acetyl-CoA carboxylase inhibitors attenuate WNT and Hedgehog signaling and suppress pancreatic tumor growth

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis

Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas

GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3

Targeting protein homeostasis with nelfinavir/salinomycin dual therapy effectively induces death of mTORC1 hyperactive cells

USP14 de-ubiquitinates vimentin and miR-320a modulates USP14 and vimentin to contribute to malignancy in gastric cancer cells

The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis

The adenosine A2b receptor promotes tumor progression of bladder urothelial carcinoma by enhancing MAPK signaling pathway

Genetic heterogeneity in leiomyomas of deep soft tissue

Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis

Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics

Survival differences of CIMP subtypes integrated with CNA information in human breast cancer

EMT-like circulating tumor cells in ovarian cancer patients are enriched by platinum-based chemotherapy

Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer

Hematopoietic stem/progenitor cells are less prone to undergo apoptosis than lymphocytes despite similar DNA damage response

Importance of the plasma soluble HLA-G levels for prognostic stratification with traditional prognosticators in colorectal cancer

Gut microbiota drives the attenuation of dextran sulphate sodium-induced colitis by Huangqin decoction

The tumor suppressor interferon regulatory factor 8 inhibits β-catenin signaling in breast cancers, but is frequently silenced by promoter methylation

TIPE3 protein promotes breast cancer metastasis through activating AKT and NF-κB signaling pathways

HER2 and EGFR amplification and expression in urothelial carcinoma occurs in distinct biological and molecular contexts

Micro RNA-19a interferes with IL-10 expression in peripheral dendritic cells of patients with nasal polyposis

The role of postoperative radiotherapy (PORT) in combined small cell lung cancer (C-SCLC)

Expression characteristic of CXCR1 in different breast tissues and the relevance between its expression and efficacy of neo-adjuvant chemotherapy in breast cancer

Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4⁺ T cells of patients with systemic lupus erythematosus

Co-expression network analysis identified six hub genes in association with metastasis risk and prognosis in hepatocellular carcinoma

Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice

P2X7 receptor and NLRP3 inflammasome activation in head and neck cancer

Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells

Comprehensive analysis of interleukin-8 gene polymorphisms and periodontitis susceptibility

Low concentration of BPA induces mice spermatocytes apoptosis via GPR30

Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration

WP1130 attenuates cisplatin resistance by decreasing P53 expression in non–small cell lung carcinomas

Predictive and prognostic value of folate receptor-positive circulating tumor cells in small cell lung cancer patients treated with first-line chemotherapy

miR-302b inhibits cancer-related inflammation by targeting ERBB4, IRF2 and CXCR4 in esophageal cancer

Interleukin-37 mediates the antitumor activity in colon cancer through β-catenin suppression

The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients

Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced non-small cell lung cancer in Chinese population: A retrospective study

HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372

Transforming growth factor-β1 promotes breast cancer metastasis by downregulating miR-196a-3p expression

Somatostatin receptor 2A in gliomas: Association with oligodendrogliomas and favourable outcome

Novel transcription-induced fusion RNAs in prostate cancer

Extracellular signal-regulated kinase 8-mediated NF-κB activation increases sensitivity of human lung cancer cells to arsenic trioxide

Methotrexate-cytarabine-dexamethasone combination chemotherapy with or without rituximab in patients with primary central nervous system lymphoma

In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma

The integrative metabolomic-transcriptomic landscape of glioblastome multiforme

Next-generation sequencing reveals microRNA markers of adrenocortical tumors malignancy

Identification of aberrantly expressed long non-coding RNAs in stomach adenocarcinoma

Diagnostic and prognostic values of endothelial-cell-specific molecule-1 with malignant pleural effusions in patients with non-small cell lung cancer

Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by β1 integrin/JNK co-targeting

BMX/Etk promotes cell proliferation and tumorigenicity of cervical cancer cells through PI3K/AKT/mTOR and STAT3 pathways

Oscillating expression of interleukin-16 in multiple myeloma is associated with proliferation, clonogenic growth, and PI3K/NFKB/MAPK activation

Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium

Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer

Role of intravoxel incoherent motion MR imaging in preoperative assessing HER2 status of gastric cancers

Inflammatory microRNA-194 and -515 attenuate the biosynthesis of chondroitin sulfate during human intervertebral disc degeneration

Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer

EMT circulating tumor cells detected by cell-surface vimentin are associated with prostate cancer progression

Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice

Multiplex PCR approach to simultaneously identify several mutations in fine needle cytology thyroid samples

Prediction of the aquatic toxicity of aromatic compounds to tetrahymena pyriformis through support vector regression

Outcomes of patients with inflammatory breast cancer by hormone receptor- and HER2-defined molecular subtypes: A population-based study from the SEER program

Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells

Oroxylin A inhibits the generation of Tregs in non-small cell lung cancer

LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis

Comparative analysis of diagnostic performance, feasibility and cost of different test-methods for thyroid nodules with indeterminate cytology

Real time near-infrared Raman spectroscopy for the diagnosis of nasopharyngeal cancer

Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity

Galectin-3 acts as an angiogenic switch to induce tumor angiogenesis via Jagged-1/Notch activation

IKBKE regulates cell proliferation and epithelial–mesenchymal transition of human malignant glioma via the Hippo pathway

Comparison of the efficacy among multiple chemotherapeutic interventions combined with radiation therapy for patients with cervix cancer after surgery: A network meta-analysis

MiR-650 represses high-risk non-metastatic colorectal cancer progression via inhibition of AKT2/GSK3β/E-cadherin pathway

NKp30 expression is a prognostic immune biomarker for stratification of patients with intermediate-risk acute myeloid leukemia

Impact of postmastectomy radiation therapy in T1-2 breast cancer patients with 1-3 positive axillary lymph nodes

Cancer killers in the human gut microbiota: diverse phylogeny and broad spectra

Role of transgelin-2 in diabetes-associated pancreatic ductal adenocarcinoma

Evaluation of cumulative prognostic score based on pretreatment plasma fibrinogen and serum albumin levels in patients with newly diagnosed high-grade gliomas

Effect of renal embolization in patients with synchronous metastatic renal cell carcinoma: a retrospective comparison of cytoreductive nephrectomy and systemic medical therapy

Dietary grape seed proanthocyanidins inactivate regulatory T cells by promoting NER-dependent DNA repair in dendritic cells in UVB-exposed skin

Development of a novel score for the prediction of hospital mortality in patients with severe sepsis: the use of electronic healthcare records with LASSO regression

Assessment of GSK1904529A as a promising anti-osteosarcoma agent

The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/ MDA5 activation

EGFR G796D mutation mediates resistance to osimertinib

Efficacy of epidermal growth factor receptor–tyrosine kinase inhibitors for lung squamous carcinomas harboring EGFR mutation: A multicenter study and pooled analysis of published reports

Clinical evaluation of integrated panel testing by next-generation sequencing for somatic mutations in neuroblastomas with MYCN unamplification

Relationship between expression of PD-L1 and tumor angiogenesis, proliferation, and invasion in glioma

HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1α and HIF-2α balance in renal cell carcinoma

Amyloid precursor like protein-1 promotes JNK-mediated cell migration in Drosophila

Suppression of LPS-induced inflammatory responses by the hydroxyl groups of dexamethasone

Contrast media enhancement reduction predicts tumor response to presurgical molecular-targeting therapy in patients with advanced renal cell carcinoma

Increased expression of IRF8 in tumor cells inhibits the generation of Th17 cells and predicts unfavorable survival of diffuse large B cell lymphoma patients

The detection and significance of EGFR and BRAF in cell-free DNA of peripheral blood in NSCLC

Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin

DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors

Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway

The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells

Intra-tumour molecular heterogeneity of clear cell renal cell carcinoma reveals the diversity of the response to targeted therapies using patient-derived xenograft models

An esophageal squamous cell carcinoma classification system that reveals potential targets for therapy

Nomogram predicts survival benefit from preoperative radiotherapy for non-metastatic breast cancer: A SEER-based study

Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation

FAM3A mediates PPARγ's protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress

Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- β1-SMAD3-ID1 signaling pathway

Does the ¹H-NMR plasma metabolome reflect the host-tumor interactions in human breast cancer?

Genome-wide analysis of aberrantly expressed lncRNAs and miRNAs with associated co-expression and ceRNA networks in β-thalassemia and hereditary persistence of fetal hemoglobin

Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines

Acetylsalicylic acid inhibits the growth of melanoma tumors via SOX2-dependent-PAF-R-independent signaling pathway

Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells

Local application of bacteria improves safety of Salmonella -mediated tumor therapy and retains advantages of systemic infection

Therapeutic utility of natural estrogen receptor beta agonists on ovarian cancer

The effect of CA125 on metastasis of ovarian cancer: old marker new function

Cryptotanshinone inhibits proliferation yet induces apoptosis by suppressing STAT3 signals in renal cell carcinoma

Prognostic role of lncRNA TUG1 for cancer outcome: Evidence from 840 cancer patients

Association between three VEGF polymorphisms and renal cell carcinoma susceptibility: a meta-analysis

CDKN2A methylation in esophageal cancer: a meta-analysis

Independent and joint effects of tea and milk consumption on oral cancer among non-smokers and non-drinkers: a case-control study in China

Predictable biomarkers of developing lymphoma in patients with Sjögren syndrome: a nationwide population-based cohort study

A multicenter matched case-control analysis on seven polymorphisms from HMGB1 and RAGE genes in predicting hepatocellular carcinoma risk

Preoperative inflammation markers and IDH mutation status predict glioblastoma patient survival

Association between ERCC2 Lys751Gln polymorphism and the risk of pancreatic cancer, especially among Asians: evidence from a meta-analysis

Endoscopic diagnosis of primary anorectal melanoma

A retrospective analysis of the utility of endocervical curettage in screening population

Increased serum resistin level is associated with coronary heart disease

A phase II prospective study of the “Sandwich” protocol, L-asparaginase, cisplatin, dexamethasone and etoposide chemotherapy combined with concurrent radiation and cisplatin, in newly diagnosed, I/II stage, nasal type, extranodal natural killer/T-cell lymphoma

The awakening of the CDK10/Cyclin M protein kinase

Structural homologies between phenformin, lipitor and gleevec aim the same metabolic oncotarget in leukemia and melanoma

miR-133b, a particular member of myomiRs, coming into playing its unique pathological role in human cancer

Epidermal growth factor receptor (EGFR): A rising star in the era of precision medicine of lung cancer

Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors

Micrornas in prostate cancer: an overview

Characterization of potential driver mutations involved in human breast cancer by computational approaches

Clinicopathologic significance and prognostic value of Ki-67 expression in patients with gastric cancer: a meta-analysis

Integration of phytochemicals and phytotherapy into cancer precision medicine

Advanced alveolar soft part sarcoma responds to apatinib

Correction: Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development