RUNX1 and breast cancer

Pannexin1 knockout and blockade reduces ischemic stroke injury in female, but not in male mice

Zerumbone ameliorates high-fat diet-induced adiposity by restoring AMPK-regulated lipogenesis and microRNA-146b/SIRT1-mediated adipogenesis

Association of miR-608 rs4919510 polymorphism and cancer risk: a meta-analysis based on 13,664 subjects

LoLoPicker: detecting low allelic-fraction variants from low-quality cancer samples

RARα2 and PML-RAR similarities in the control of basal and retinoic acid induced myeloid maturation of acute myeloid leukemia cells

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

Comparative study of cisplatin-based definitive concurrent chemoradiotherapy with S-1 versus paclitaxel for unresectable locally advanced esophageal squamous cell carcinoma

Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells

The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia

hMAGEA2 promotes progression of breast cancer by regulating Akt and Erk1/2 pathways

Gene-modified NK-92MI cells expressing a chimeric CD16-BB-ζ or CD64-BB-ζ receptor exhibit enhanced cancer-killing ability in combination with therapeutic antibody

Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma

YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma

Metastasis-associated protein 3 in colorectal cancer determines tumor recurrence and prognosis

Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer

Synthesis and evaluation of anthranilamide-based derivatives as FXa inhibitors

Are pretreatment neutrophil-lymphocyte ratio and platelet-lymphocyte ratio useful in predicting the outcomes of patients with small-cell lung cancer?

Nomograms for predicting progression and efficacy of post-operation radiotherapy in IIIA-pN2 non-small cell lung cancer patients

Interleukin-10 rs1800896 polymorphism is associated with increased head and neck cancer risk but not associated with its clinical stages

MiRNA profiling of gastrointestinal stromal tumors by next-generation sequencing

The relevance of a low JAK2^V617F allele burden in clinical practice: a monocentric study

Targeting of the breast cancer microenvironment with a potent and linkable oxindole based antiangiogenic small molecule

XPG gene polymorphisms and cancer susceptibility: evidence from 47 studies

Carcinoma-specific expression of P2Y₁₁ receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells

Distinct MDCT imaging features to differential diagnosis of hepatic paragonimiasis and small hepatocellular carcinoma

Renal sympathetic denervation guided by renal nerve stimulation to treat ventricular arrhythmia in CKD patients with ICD

PPARGC1A rs3736265 G>A polymorphism is associated with decreased risk of type 2 diabetes mellitus and fasting plasma glucose level

Transcriptome profiling reveals miR-9-3p as a novel tumor suppressor in gastric cancer

Increased risk of brain metastases in women with breast cancer and p16 expression in metastatic lymph-nodes

Upregulation of calprotectin in mild IgE-mediated ovalbumin hypersensitivity

MiR-146a negatively regulates dectin-1-induced inflammatory responses

An inverse association between tea consumption and colorectal cancer risk

NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway

A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes

The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo

Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma

High expression of B7-H6 in human glioma tissues promotes tumor progression

The N-terminal polypeptide derived from viral macrophage inflammatory protein II reverses breast cancer epithelial-to-mesenchymal transition via a PDGFRα-dependent mechanism

Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multi-parametric magnetic resonance imaging

Respiratory status determines the effect of emodin on cell viability

Prognostic value of circulating endothelial cells in metastatic colorectal cancer

Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma

Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma

Detection of a combination of serum IgG and IgA antibodies against selected mycobacterial targets provides promising diagnostic signatures for active TB

Metformin inhibits proliferation and growth hormone secretion of GH3 pituitary adenoma cells

Anti-tumor activity of an immunotoxin (TGFα-PE38) delivered by attenuated Salmonella typhimurium

Impact of interaction between the G870A and EFEMP1 gene polymorphism on glioma risk in Chinese Han population

Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit

Contrast-enhanced ultrasound evaluation of pancreatic cancer xenografts in nude mice after irradiation with sub-threshold focused ultrasound for tumor ablation

Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines

A prospective, open-label, multicenter, observational study to evaluate the efficacy and safety of bortezomib-melphalan-prednisone as initial treatment for autologous stem cell transplantation-ineligible patients with multiple myeloma

Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1

Involvement of Polo-like kinase 1 (Plk1) in quiescence regulation of cancer stem-like cells of the gastric cancer cell lines

Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma

Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development

Elevated CD147 expression is associated with shorter overall survival in non-small cell lung cancer

Modulation of the inwardly rectifying potassium channel Kir4.1 by the pro-invasive miR-5096 in glioblastoma cells

Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency

Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway

KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling

Clinical and biological features of neuroblastic tumors: A comparison of neuroblastoma and ganglioneuroblastoma

Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma

CRISPR/Cas9-mediated ApoE^-/- and LDLR^-/- double gene knockout in pigs elevates serum LDL-C and TC levels

Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels, toxicity of high-dose methotrexate, and outcome of pediatric acute lymphoblastic leukemia

Stereochemical preference toward oncotarget: Design, synthesis and in vitro anticancer evaluation of diastereomeric β-lactams

Negative regulation of tumor-infiltrating NK cell in clear cell renal cell carcinoma patients through the exosomal pathway

Effect of interrupted time during intensity modulated radiation therapy on survival outcomes in patients with nasopharyngeal cancer

Maintenance treatment of Uracil and Tegafur (UFT) in responders following first-line fluorouracil-based chemotherapy in metastatic gastric cancer: a randomized phase II study

Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma

The combination of early treatment response and ypT stage is a novel metric to stage rectal cancer patients treated with neoadjuvant chemoradiotherapy

Texture analysis of intermediate-advanced hepatocellular carcinoma: prognosis and patients’ selection of transcatheter arterial chemoembolization and sorafenib

Outcome of patients treated for myelodysplastic syndromes without deletion 5q after failure of lenalidomide therapy

Clinical parameters to guide decision-making in elderly metastatic colorectal cancer patients treated with intensive cytotoxic and anti-angiogenic therapy

Comparison between ultra-high and conventional mono b-value DWI for preoperative glioma grading

Short-term efficacy of different chemotherapy regimens in the treatment of advanced gastric cancer: a network meta-analysis

Quantification and expert evaluation of evidence for chemopredictive biomarkers to personalize cancer treatment

Effects of CD20+ B-cell infiltration into allografts on kidney transplantation outcomes: a systematic review and meta-analysis

Regulatory functional territory of PLK-1 and their substrates beyond mitosis

Concurrent chemo-radiotherapy with S-1 as an alternative therapy for elderly Chinese patients with non-metastatic esophageal squamous cancer: evidence based on a systematic review and meta-analysis

Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target

Emerging proteomics biomarkers and prostate cancer burden in Africa

Mesenchymal stem cells and their therapeutic applications in inflammatory bowel disease

Combination therapy in combating cancer

Functional and therapeutic significance of EZH2 in urological cancers

Clinical features and surgical treatment of sacral schwannomas

Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease: a case report and review of the literature