Influence of aging on the activity of mice Sca-1⁺CD31⁻ cardiac stem cells

How does white matter microstructure differ between the vascular and amnestic mild cognitive impairment?

Gastric acid response to acute exposure to hypergravity

Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire^-/- mice

Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling

Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers

Non-myogenic tumors display altered expression of dystrophin (DMD) and a high frequency of genetic alterations

Prognostic impact of MYH9 expression on patients with acute myeloid leukemia

4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression

Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC

IGFBP2 expression predicts IDH-mutant glioma patient survival

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett’s-like esophagus

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers

Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds

BRAF-activated LncRNA functions as a tumor suppressor in papillary thyroid cancer

Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade

Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?

Prognostic significance of BRCA mutations in ovarian cancer: an updated systematic review with meta-analysis

Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysis

Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy

Paradoxes in thyroid carcinoma treatment: analysis of the SEER database 2010-2013

AAV-Mediated angiotensin 1-7 overexpression inhibits tumor growth of lung cancer in vitro and in vivo

Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis

Deletion of 8p is an independent prognostic parameter in prostate cancer

Association between three functional microRNA polymorphisms (miR-499 rs3746444, miR-196a rs11614913 and miR-146a rs2910164) and breast cancer risk: a meta-analysis

Hepatic resection after transarterial chemoembolization increases overall survival in large/multifocal hepatocellular carcinoma: a retrospective cohort study

Immunological effects of nilotinib prophylaxis after allogeneic stem cell transplantation in patients with advanced chronic myeloid leukemia or philadelphia chromosome-positive acute lymphoblastic leukemia

Targeting tachykinin receptors in neuroblastoma

Evolutionary biologic changes of gut microbiota in an ‘adenoma-carcinoma sequence’ mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine

Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis

New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status

Is the positivity of estrogen receptor or progesterone receptor different between type 1 and type 2 endometrial cancer?

Human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis via regulation of B lymphocyte maturation

Pathologic stratification of operable lung adenocarcinoma using radiomics features extracted from dual energy CT images

Expression of truncated bile salt-dependent lipase variant in pancreatic pre-neoplastic lesions

Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth

EZH2 overexpression is associated with poor prognosis in patients with glioma

Upregulation of microRNA-524-5p enhances the cisplatin sensitivity of gastric cancer cells by modulating proliferation and metastasis via targeting SOX9

Acquired resistance to BRAF inhibition in BRAF^V600E mutant gliomas

Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation

A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice

TP53 mutations, expression and interaction networks in human cancers

Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression

PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population

PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth

Accumulated promoter methylation as a potential biomarker for esophageal cancer

Cholesterol import and steroidogenesis are biosignatures for gastric cancer patient survival

MicroRNA-206 is involved in the pathogenesis of ulcerative colitis via regulation of adenosine A3 receptor

Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer

Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells

Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma

Ion channels in control of pancreatic stellate cell migration

Novel risk models for early detection and screening of ovarian cancer

Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication

Circular RNA ZNF609 functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-150-5p in Hirschsprung’s disease

M2-like tumor-associated macrophages drive vasculogenic mimicry through amplification of IL-6 expression in glioma cells

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq

TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development

Baicalein reduces angiogenesis in the inflammatory microenvironment via inhibiting the expression of AP-1

Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness

Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways

PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration

Hierarchical investigating the predictive value of p53, COX2, EGFR, nm23 in the post-operative patients with colorectal carcinoma

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism

Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signaling

Preclinical study of cinobufagin as a promising anti-colorectal cancer agent

TGFβ1 overexpression is associated with improved survival and low tumor cell proliferation in patients with early-stage pancreatic ductal adenocarcinoma

New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate

Platelet-lymphocyte ratio acts as an indicator of poor prognosis in patients with breast cancer

Chemopreventive effects of 5-aminosalicylic acid on inflammatory bowel disease-associated colorectal cancer and dysplasia: a systematic review with meta-analysis

MET expression and copy number status in clear-cell renal cell carcinoma: prognostic value and potential predictive marker

Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival

Impact of hematological inflammatory markers on clinical outcome in patients with salivary duct carcinoma: a multi-institutional study in Japan

Spermidine/spermine N¹-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells

The change of HCN1/HCN2 mRNA expression in peripheral nerve after chronic constriction injury induced neuropathy followed by pulsed electromagnetic field therapy

The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry

Molecular mechanism of hepatitis B virus (HBV) on suppression of raf kinase inhibitor protein (RKIP) expression

Efficacy and safety of angiogenesis inhibitors in small-cell lung cancer

The association between the TP53 Arg72Pro polymorphism and colorectal cancer: An updated meta-analysis based on 32 studies

TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population

Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia

Hyperglycemia triggers HIPK2 protein degradation

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients

Gene expression profiling of hematologic malignant cell lines resistant to oncolytic virus treatment

MiR-146a rs2910164 polymorphism and head and neck carcinoma risk: a meta-analysis based on 10 case-control studies

Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain

HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs

Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer

Association of smoking status with prognosis in bladder cancer: A meta-analysis

Cancer-associated fibroblasts promote cancer cell growth through a miR-7-RASSF2-PAR-4 axis in the tumor microenvironment

Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts

Genomic and transcriptomic characterization of skull base chordoma

Has aidi injection the attenuation and synergistic efficacy to gemcitabine and cisplatin in non-small cell lung cancer? A meta-analysis of 36 randomized controlled trials

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer

Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study

Cancer initiating-cells are enriched in the CA9 positive fraction of primary cervix cancer xenografts

TFDP3 confers chemoresistance in minimal residual disease within childhood T-cell acute lymphoblastic leukemia

DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients

LncRNA H19 inhibits autophagy by epigenetically silencing of DIRAS3 in diabetic cardiomyopathy

Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells

PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide

Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling

Targeting tissue factor as a novel therapeutic oncotarget for eradication of cancer stem cells isolated from tumor cell lines, tumor xenografts and patients of breast, lung and ovarian cancer

Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes

GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway

Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia

Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway

Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma

Hemoglobin level trajectories in the early treatment period are related with survival outcomes in patients with breast cancer

Risk stratification of thyroid nodules with Bethesda category III results on fine-needle aspiration cytology: The additional value of acoustic radiation force impulse elastography

Stag3 regulates microtubule stability to maintain euploidy during mouse oocyte meiotic maturation

Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma

Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis

The metastasis suppressor CD82/KAI1 inhibits fibronectin adhesion-induced epithelial-to-mesenchymal transition in prostate cancer cells by repressing the associated integrin signaling

High lncRNA H19 expression as prognostic indicator: data mining in female cancers and polling analysis in non-female cancers

Suppression of immune regulatory cells with combined therapy of celecoxib and sunitinib in renal cell carcinoma

p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription

The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition

NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

Prognostic value of whole-body SUVmax of nodal and extra-nodal lesions detected by ¹⁸F-FDG PET/CT in extra-nodal NK/T-cell lymphoma

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial

Metavir and FIB-4 scores are associated with patient prognosis after curative hepatectomy in hepatitis B virus-related hepatocellular carcinoma: a retrospective cohort study at two centers in China

Necessity of organized low-dose computed tomography screening for lung cancer: From epidemiologic comparisons between China and the Western nations

Optimal radiation dose for patients with one to three lymph node positive breast cancer following breast-conserving surgery and anthracycline plus taxane-based chemotherapy: A retrospective multicenter analysis (KROG 1418)

Type I insulin-like growth factor receptor signaling in hematological malignancies

Sirtuins in glucose and lipid metabolism

Outcomes in adult critically Ill cancer patients with and without neutropenia: a systematic review and meta-analysis of the Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)

Associations of P16^INK4a promoter hypermethylation with squamous intra-epithelial lesion, cervical cancer and their clinicopathological features: a meta-analysis

Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion

Triple-negative breast cancer: is there a treatment on the horizon?

Long non-coding RNAs in anti-cancer drug resistance

Role of long noncoding RNA UCA1 as a common molecular marker for lymph node metastasis and prognosis in various cancers: a meta-analysis

Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis