Troponin-I enhances and is required for oncogenic overgrowth

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression

The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging

Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle

Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivo

Association of genetic variations in the Wnt signaling pathway genes with myocardial infarction susceptibility in Chinese Han population

Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer

In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses

Integrated analysis miRNA and mRNA profiling in patients with severe oligozoospermia reveals miR-34c-3p downregulates PLCXD3 expression

Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer

Minocycline promotes the generation of dendritic cells with regulatory properties

Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers

KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth

A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine

IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma

Modulation of miR-21 signaling by MPS1 in human glioblastoma

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures

Consensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based “starvation” strategies in BRCA1 carriers

Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer

Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma

Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancer

Decreased radiation doses to tongue with “stick-out” tongue position over neutral tongue position in head and neck cancer patients who refused or could not tolerate an intraoral device (bite-block, tongue blade, or mouthpiece) due to trismus, gag reflex, or discomfort during intensity-modulated radiation therapy

An appraisal of drug development timelines in the Era of precision oncology

PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

Molecular mechanisms of OLIG2 transcription factor in brain cancer

Development of a sequential workflow based on LC-PRM for the verification of endometrial cancer protein biomarkers in uterine aspirate samples

Combination therapy with copanlisib and ABL tyrosine kinase inhibitors against Philadelphia chromosome-positive resistant cells

TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer

KRAS^G12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway

Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules

CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin

Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer

Correlation between overall survival and differential plasma and tissue tumor marker expression in nasopharyngeal carcinoma patients with different sites of organ metastasis

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer

Prognostic effect of liver metastasis in lung cancer patients with distant metastasis

MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2

The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth

Effect of perineoplasm perinephric adipose tissues on migration of clear cell renal cell carcinoma cells: a potential role of WNT signaling

PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients

CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients

Volumetric modulated arc therapy for thoracic node metastases: a safe and effective treatment for a neglected disease

Tristetraprolin functions in cytoskeletal organization during mouse oocyte maturation

Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy

IL-17E synergizes with EGF and confers in vitro resistance to EGFR-targeted therapies in TNBC cells

Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies

Prexasertib, a Chk1/Chk2 inhibitor, increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia

The prognostic value of a seven-microRNA classifier as a novel biomarker for the prediction and detection of recurrence in glioma patients

Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43

Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer

Gelsolin suppresses gastric cancer metastasis through inhibition of PKR-p38 signaling

Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells

Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety

Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies

Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling

Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia

miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways

Treatment with an SLC12A1 antagonist inhibits tumorigenesis in a subset of hepatocellular carcinomas

The mutational profile and infiltration pattern of murine MLH1^-/- tumors: concurrences, disparities and cell line establishment for functional analysis

ZKSCAN3 promotes bladder cancer cell proliferation, migration, and invasion

Aberrant transcriptional networks in step-wise neurogenesis of paroxysmal kinesigenic dyskinesia-induced pluripotent stem cells

Expression of glutamine metabolism-related proteins in thyroid cancer

AMP-activated protein kinase is involved in the activation of the Fanconi anemia/BRCA pathway in response to DNA interstrand crosslinks

AMPKα1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2

Impact of sex, age, and ethnicity/race on the survival of patients with rectal cancer in the United States from 1988 to 2012

Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL

Decreased Dp71 expression is associated with gastric adenocarcinoma prognosis

The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy

miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion

Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model

An assessment of factors associated with quality of randomized controlled trials for smoking cessation

Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of K_v1.3 channels and T cell responsiveness

MicroRNA-155 is a potential molecular marker of natural killer/T-cell lymphoma

Circulating microRNA profiles in plasma: identification of miR-224 as a novel diagnostic biomarker in hepatocellular carcinoma independent of hepatic function

PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence

Reduced miR-550a-3p leads to breast cancer initiation, growth, and metastasis by increasing levels of ERK1 and 2

c-CBL regulates melanoma proliferation, migration, invasion and the FAK-SRC-GRB2 nexus

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

Characteristics of human papillomaviruses infection in men with genital warts in Shanghai

Percutaneous intraductal radiofrequency ablation in the management of unresectable Bismuth types III and IV hilar cholangiocarcinoma

High dose and compartmental target volume may improve patient outcome after radiotherapy for pelvic bone metastases from hepatocellular carcinoma

Virus infection facilitates the development of severe pneumonia in transplant patients with hematologic malignancies

Interplay between chronic kidney disease (CKD) and upper tract urothelial carcinomas (UUC): foe or friend?

Important molecular genetic markers of colorectal cancer

Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer

Targeting BET bromodomain proteins in solid tumors

New insights into the unfolded protein response in stem cells

DMET^TM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine

Prostate cancer and the unfolded protein response

N-acetylgalactosaminyltransferases in cancer

Cancer subtypes classification using long non-coding RNA