New dimension in therapeutic targeting of BCL-2 family proteins

Deubiquitinases in cancer

Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype?

Use of tilapia piscidin 3 (TP3) to protect against MRSA infection in mice with skin injuries

Assessment and diagnostic relevance of novel serum biomarkers for early decision of ST-elevation myocardial infarction

Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding

PI3K/AKT/mTOR pathway plays a major pathogenetic role in glycogen accumulation and tumor development in renal distal tubules of rats and men

Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer

Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling

Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma

miR-497 and miR-34a retard lung cancer growth by co-inhibiting cyclin E1 (CCNE1)

MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5

MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells

MiR-1 downregulation correlates with poor survival in clear cell renal cell carcinoma where it interferes with cell cycle regulation and metastasis

MicroRNA-212 suppresses tumor growth of human hepatocellular carcinoma by targeting FOXA1

Massive parallel IGHV gene sequencing reveals a germinal center pathway in origins of human multiple myeloma

CDC20 maintains tumor initiating cells

Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer

Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia

Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation

Deregulation of focal adhesion pathway mediated by miR-659-3p is implicated in bone marrow infiltration of stage M neuroblastoma patients

Prognostic value of MET protein overexpression and gene amplification in locoregionally advanced nasopharyngeal carcinoma

Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER)

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer

Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies

HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells

Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma

Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients

Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer

Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma

Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

Nimotuzumab increases the anti-tumor effect of photodynamic therapy in an oral tumor model

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy

Cyr61 as mediator of Src signaling in triple negative breast cancer cells

Highly sensitive and specific novel biomarkers for the diagnosis of transitional bladder carcinoma

Immunoglobulin-like transcript 4 promotes tumor progression and metastasis and up-regulates VEGF-C expression via ERK signaling pathway in non-small cell lung cancer

A novel Golgi protein (GOLPH2)-regulated oncolytic adenovirus exhibits potent antitumor efficacy in hepatocellular carcinoma

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon

Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer

Enhanced tumorigenicity by mitochondrial DNA mild mutations

SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3

MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis

A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy

Gene expression in “young adult type” breast cancer: a retrospective analysis

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

YBX1/YB-1 induces partial EMT and tumourigenicity through secretion of angiogenic factors into the extracellular microenvironment

Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studies

Targeted sequencing with enrichment PCR: a novel diagnostic method for the detection of EGFR mutations

Impact of aging on calcium influx and potassium channel characteristics of T lymphocytes

Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors

Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation

A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis

Characterization of tumor infiltrating natural killer cell subset