DNA replication stress as an Achilles’ heel of cancer
DNA replication stress as an Achilles’ heel of cancer |
|
https://doi.org/10.18632/oncotarget.3147
Caterina Da-Rè,
and Thanos D. Halazonetis
|
| 1-2 |
Simplify p53: just an activator
Simplify p53: just an activator |
|
https://doi.org/10.18632/oncotarget.3032
Kurt Engeland
|
| 3-4 |
Mcl-1 and tumor cell persistence
Mcl-1 and tumor cell persistence |
|
https://doi.org/10.18632/oncotarget.3035
Lukas W. Pfannenstiel,
and Brian R. Gastman
|
| 5-6 |
MicroRNAs in B-cells: from normal differentiation to treatment of malignancies
MicroRNAs in B-cells: from normal differentiation to treatment of malignancies |
|
https://doi.org/10.18632/oncotarget.3057
Sara Correia Marques,
Maria Bach Laursen,
Julie Støve Bødker,
Malene Krag Kjeldsen,
Steffen Falgreen,
Alexander Schmitz,
Martin Bøgsted,
Hans Erik Johnsen,
and Karen Dybkaer
|
| 7-25 |
An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein
An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein |
|
https://doi.org/10.18632/oncotarget.3083
Martin F. Orth,
Alex Cazes,
Elke Butt,
and Thomas G. P. Grunewald
|
| 26-42 |
Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism
Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism |
|
https://doi.org/10.18632/oncotarget.2723
Siyoung Cho,
Miook Cho,
Juewon Kim,
Matt Kaeberlein,
Sang Jun Lee,
and Yousin Suh
|
| 43-55 |
Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer
Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer |
|
https://doi.org/10.18632/oncotarget.2695
Frank P. Vendetti,
Michael Topper,
Peng Huang,
Irina Dobromilskaya,
Hariharan Easwaran,
John Wrangle,
Stephen B. Baylin,
J. T. Poirier,
and Charles M. Rudin
|
| 56-70 |
Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells
Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells |
|
https://doi.org/10.18632/oncotarget.2698
Vincenzo Desiderio,
Petros Papagerakis,
Virginia Tirino,
Li Zheng,
Margarite Matossian,
Mark E. Prince,
Francesca Paino,
Luigi Mele,
Federica Papaccio,
Roberta Montella,
Gianpaolo Papaccio,
and Silvana Papagerakis
|
| 71-84 |
WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1
WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 |
|
https://doi.org/10.18632/oncotarget.2765
Yi-Fang Chang,
Ya-Fen Hsu,
Pei-Ting Chiu,
Wei-Jan Huang,
Shiu-Wen Huang,
George Ou,
Joen-Rong Sheu,
and Ming-Jen Hsu
|
| 85-100 |
Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma
Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.2684
Xiao-Yun Zhang,
Minle Li,
Kai Sun,
Xiao-Jie Chen,
Jian Meng,
Lifang Wu,
Ping Zhang,
Xuemei Tong,
and Wei-Wen Jiang
|
| 101-115 |
RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification
RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification |
|
https://doi.org/10.18632/oncotarget.2699
Paulina Ćwiek,
Zaira Leni,
Fabiana Salm,
Valeriya Dimitrova,
Beata Styp-Rekowska,
Gianpaolo Chiriano,
Michael Carroll,
Katrin Höland,
Valentin Djonov,
Leonardo Scapozza,
Patrick Guiry,
and Alexandre Arcaro
|
| 116-129 |
Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells
Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells |
|
https://doi.org/10.18632/oncotarget.2766
Takumi Shiraishi,
James E. Verdone,
Jessie Huang,
Ulf D. Kahlert,
James R. Hernandez,
Gonzalo Torga,
Jelani C. Zarif,
Tamir Epstein,
Robert Gatenby,
Annemarie McCartney,
Jennifer H. Elisseeff,
Steven M. Mooney,
Steven S. An,
and Kenneth J. Pienta
|
| 130-143 |
CIP2A is an Oct4 target gene involved in head and neck squamous cell cancer oncogenicity and radioresistance
CIP2A is an Oct4 target gene involved in head and neck squamous cell cancer oncogenicity and radioresistance |
|
https://doi.org/10.18632/oncotarget.2670
Sami Ventelä,
Eleonora Sittig,
Leni Mannermaa,
Juho-Antti Mäkelä,
Jarmo Kulmala,
Eliisa Löyttyniemi,
Leena Strauss,
Olli Cárpen,
Jorma Toppari,
Reidar Grénman,
and Jukka Westermarck
|
| 144-158 |
Dendritic cells respond to nasopharygeal carcinoma cells through annexin A2-recognizing DC-SIGN
Dendritic cells respond to nasopharygeal carcinoma cells through annexin A2-recognizing DC-SIGN |
|
https://doi.org/10.18632/oncotarget.2700
Pin-Zhir Chao,
Ming-Shium Hsieh,
Chao-Wen Cheng,
Tin-Jui Hsu,
Yun-Tien Lin,
Chang-Hao Lai,
Chen-Chung Liao,
Wei-Yu Chen,
Ting-Kai Leung,
Fei-Peng Lee,
Yung-Feng Lin,
and Chien-Ho Chen
|
| 159-170 |
Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57
Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57 |
|
https://doi.org/10.18632/oncotarget.2767
Xuekai Zhu,
Shruthi Prasad,
Simone Gaedicke,
Michael Hettich,
Elke Firat,
and Gabriele Niedermann
|
| 171-184 |
A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma
A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma |
|
https://doi.org/10.18632/oncotarget.2688
Jingyu Zhu,
Man Wang,
Yang Yu,
Huixin Qi,
Kunkun Han,
Juan Tang,
Zubin Zhang,
Yuanying Zeng,
Biyin Cao,
Chunhua Qiao,
Hongjian Zhang,
Tingjun Hou,
and Xinliang Mao
|
| 185-195 |
Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma
Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma |
|
https://doi.org/10.18632/oncotarget.2768
Ann M. Lozier,
Maria E. Rich,
Anissa Pedersen Grawe,
Anderson S. Peck,
Ping Zhao,
Anthony Ting-Tung Chang,
Jeffrey P. Bond,
and Giselle Saulnier Sholler
|
| 196-206 |
Epstein-Barr virus latent membrane protein 2A suppresses the expression of HER2 via a pathway involving TWIST and YB-1 in Epstein-Barr virus-associated gastric carcinomas
Epstein-Barr virus latent membrane protein 2A suppresses the expression of HER2 via a pathway involving TWIST and YB-1 in Epstein-Barr virus-associated gastric carcinomas |
|
https://doi.org/10.18632/oncotarget.2702
Yi-wang Zhang,
Xiao-xiao Zhao,
Cui Tan,
Zhi-gang Zhang,
Ye Jiang,
Jian-ning Chen,
Hong-bo Wei,
Ling Xue,
Hai-gang Li,
Hong Du,
and Chun-kui Shao
|
| 207-220 |
Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells
Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells |
|
https://doi.org/10.18632/oncotarget.2771
Consalvo Petti,
Gabriele Picco,
Maria Luisa Martelli,
Elena Trisolini,
Enrico Bucci,
Timothy Perera,
Claudio Isella,
and Enzo Medico
|
| 221-233 |
PD-L1 is highly expressed in Enzalutamide resistant prostate cancer
PD-L1 is highly expressed in Enzalutamide resistant prostate cancer |
|
https://doi.org/10.18632/oncotarget.2703
Jennifer L. Bishop,
Alexander Sio,
Arkhjamil Angeles,
Morgan E. Roberts,
Arun A. Azad,
Kim N. Chi,
and Amina Zoubeidi
|
| 234-242 |
CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells
CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells |
|
https://doi.org/10.18632/oncotarget.2801
Shi-Jie Wang,
Hong-Yong Cui,
Yan-Mei Liu,
Pu Zhao,
Yang Zhang,
Zhi-Guang Fu,
Zhi-Nan Chen,
and Jian-Li Jiang
|
| 243-257 |
Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells
Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells |
|
https://doi.org/10.18632/oncotarget.2724
Chun-Hao Tsai,
Hsiao-Chi Tsai,
Ho-Ning Huang,
Chih-Hung Hung,
Chin-Jung Hsu,
Yi-Chin Fong,
Horng-Chaung Hsu,
Yuan-Li Huang,
and Chih-Hsin Tang
|
| 258-270 |
GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action
GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action |
|
https://doi.org/10.18632/oncotarget.2773
Qiao Jing Lew,
Kai Ling Chu,
Yi Ling Chia,
Benjamin Soo,
Jia Pei Ho,
Chew Har Ng,
Hui Si Kwok,
Cheng-Ming Chiang,
Yao Chang,
and Sheng-Hao Chao
|
| 271-287 |
MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand
MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand |
|
https://doi.org/10.18632/oncotarget.2672
Gang Liu,
Cynthia Sprenger,
Pin-Jou Wu,
Shihua Sun,
Takuma Uo,
Kathleen Haugk,
Kathryn Soriano Epilepsia,
and Stephen Plymate
|
| 288-304 |
Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation
Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation |
|
https://doi.org/10.18632/oncotarget.2786
Seong-Jun Cho,
I-Fang Teng,
Min Zhang,
Tiffany Yin,
Yong-Sam Jung,
Jin Zhang,
and Xinbin Chen
|
| 305-316 |
Mir-24-3p downregulation contributes to VP16–DDP resistance in small-cell lung cancer by targeting ATG4A
Mir-24-3p downregulation contributes to VP16–DDP resistance in small-cell lung cancer by targeting ATG4A |
|
https://doi.org/10.18632/oncotarget.2787
Banzhou Pan,
Yitian Chen,
Haizhu Song,
Yichen Xu,
Rui Wang,
and Longbang Chen
|
| 317-331 |
New mechanistic insights of integrin β1 in breast cancer bone colonization
New mechanistic insights of integrin β1 in breast cancer bone colonization |
|
https://doi.org/10.18632/oncotarget.2788
Laure Thibaudeau,
Anna V. Taubenberger,
Christina Theodoropoulos,
Boris M. Holzapfel,
Olivier Ramuz,
Melanie Straub,
and Dietmar W. Hutmacher
|
| 332-344 |
Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380
Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380 |
|
https://doi.org/10.18632/oncotarget.2814
Xiao Huang,
Mengru Cao,
Li Wang,
Shuhong Wu,
Xiaoying Liu,
Hongyu Li,
Hui Zhang,
Rui-Yu Wang,
Xiaoping Sun,
Caimiao Wei,
Keith A. Baggerly,
Jack A. Roth,
Michael Wang,
Stephen G. Swisher,
and Bingliang Fang
|
| 345-354 |
PAK6 increase chemoresistance and is a prognostic marker for stage II and III colon cancer patients undergoing 5-FU based chemotherapy
PAK6 increase chemoresistance and is a prognostic marker for stage II and III colon cancer patients undergoing 5-FU based chemotherapy |
|
https://doi.org/10.18632/oncotarget.2803
Jian Chen,
Huijun Lu,
Dongwang Yan,
Feifei Cui,
Xiaoliang Wang,
Fudong Yu,
Yingming Xue,
Xiaodong Feng,
Jingtao Wang,
Xiao Wang,
Tao Jiang,
Meng Zhang,
Senlin Zhao,
Yang Yu,
Huamei Tang,
and Zhihai Peng
|
| 355-367 |
EPB41L3, TSP-1 and RASSF2 as new clinically relevant prognostic biomarkers in diffuse gliomas
EPB41L3, TSP-1 and RASSF2 as new clinically relevant prognostic biomarkers in diffuse gliomas |
|
https://doi.org/10.18632/oncotarget.2745
Noemi Perez-Janices,
Idoia Blanco-Luquin,
Maria Teresa Tuñón,
Edurne Barba-Ramos,
Berta Ibáñez,
Idoya Zazpe-Cenoz,
Maria Teresa Martinez-Aguillo,
Berta Hernandez,
Enrique Martínez-Lopez,
Agustin F. Fernández,
Maria Roasario Mercado,
Teresa Cabada,
David Escors,
Diego Megias,
and David Guerrero-Setas
|
| 368-380 |
MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis
MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis |
|
https://doi.org/10.18632/oncotarget.2804
Ming-Yi Ho,
Chi-Ming Liang,
and Shu-Mei Liang
|
| 381-393 |
DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers
DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers |
|
https://doi.org/10.18632/oncotarget.2697
Gerwin Heller,
Corinna Altenberger,
Bianca Schmid,
Maximilian Marhold,
Erwin Tomasich,
Barbara Ziegler,
Leonhard Müllauer,
Christoph Minichsdorfer,
György Lang,
Adelheid End-Pfützenreuter,
Balazs Döme,
Britt-Madeleine Arns,
Kwun M. Fong,
Casey M. Wright,
Ian A. Yang,
Walter Klepetko,
Christoph C. Zielinski,
and Sabine Zöchbauer-Müller
|
| 394-408 |
Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1
Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1 |
|
https://doi.org/10.18632/oncotarget.2774
Barbara Jonchère,
Alexandra Vétillard,
Bertrand Toutain,
David Lam,
Anne Charlotte Bernard,
Cécile Henry,
Sophie De Carné Trécesson,
Erick Gamelin,
Philippe Juin,
Catherine Guette,
and Olivier Coqueret
|
| 409-426 |
DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1
DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1 |
|
https://doi.org/10.18632/oncotarget.2813
Jogitha Selvarajah,
Androulla Elia,
Veronica A. Carroll,
and Abdeladim Moumen
|
| 427-440 |
MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer
MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer |
|
https://doi.org/10.18632/oncotarget.2690
Wei-Yu Chen,
Shih-Yang Liu,
Yung-Sheng Chang,
Juan Juan Yin,
Hsiu-lien Yeh,
Tarek H. Mouhieddine,
Ola Hadadeh,
Wassim Abou-Kheir,
and Yen-Nien Liu
|
| 441-457 |
JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells
JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells |
|
https://doi.org/10.18632/oncotarget.2693
Shuhei Suzuki,
Masashi Okada,
Keita Shibuya,
Manabu Seino,
Atsushi Sato,
Hiroyuki Takeda,
Shizuka Seino,
Takashi Yoshioka,
and Chifumi Kitanaka
|
| 458-470 |
MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis
MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis |
|
https://doi.org/10.18632/oncotarget.2509
Katia Danza,
Simona De Summa,
Rosamaria Pinto,
Brunella Pilato,
Orazio Palumbo,
Giuseppe Merla,
Gianni Simone,
and Stefania Tommasi
|
| 471-483 |
A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer
A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer |
|
https://doi.org/10.18632/oncotarget.2861
Yao Xue,
Gaoxiang Ma,
Zhensheng Zhang,
Qiuhan Hua,
Haiyan Chu,
Na Tong,
Lin Yuan,
Chao Qin,
Changjun Yin,
Zhengdong Zhang,
and Meilin Wang
|
| 484-493 |
miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis
miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis |
|
https://doi.org/10.18632/oncotarget.2674
Tsung-Hua Hsieh,
Chia-Yi Hsu,
Cheng-Fang Tsai,
Cheng-Yu Long,
Chee-Yin Chai,
Ming-Feng Hou,
Jau-Nan Lee,
Deng-Chyang Wu,
Shao-Chun Wang,
and Eing-Mei Tsai
|
| 494-509 |
The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study
The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study |
|
https://doi.org/10.18632/oncotarget.2638
Rishil J. Kathawala,
Liuya Wei,
Nagaraju Anreddy,
Kang Chen,
Atish Patel,
Saeed Alqahtani,
Yun-Kai Zhang,
Yi-Jun Wang,
Kamlesh Sodani,
Amal Kaddoumi,
Charles R. Ashby Jr.,
and Zhe-Sheng Chen
|
| 510-521 |
Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines
Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines |
|
https://doi.org/10.18632/oncotarget.2680
Honglei Jin,
Yonghui Yu,
Young Hu,
Chris Lu,
Jingxia Li,
Jiayan Gu,
Liping Zhang,
Haishan Huang,
Dongyun Zhang,
Xue-Ru Wu,
Jimin Gao,
and Chuanshu Huang
|
| 522-536 |
Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner
Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner |
|
https://doi.org/10.18632/oncotarget.2681
Kailiang Zhang,
Xiaotian Sun,
Xuan Zhou,
Lei Han,
Luyue Chen,
Zhendong Shi,
Anling Zhang,
Minhua Ye,
Qixue Wang,
Chaoyong Liu,
Jianwei Wei,
Yu Ren,
Jingxuan Yang,
Jianning Zhang,
Peiyu Pu,
Min Li,
and Chunsheng Kang
|
| 537-546 |
Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence
Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence |
|
https://doi.org/10.18632/oncotarget.2772
Xu Zhi,
Katarzyna Lamperska,
Paweł Golusinski,
Nicholas J. Schork,
Lukasz Luczewski,
Tomasz Kolenda,
Wojciech Golusinski,
and Michal M. Masternak
|
| 547-555 |
Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia
Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia |
|
https://doi.org/10.18632/oncotarget.2785
Rene Cortese,
Isaac Almendros,
Yang Wang,
and David Gozal
|
| 556-569 |
The landscape of metastatic progression patterns across major human cancers
The landscape of metastatic progression patterns across major human cancers |
|
https://doi.org/10.18632/oncotarget.2677
Jan Budczies,
Moritz von Winterfeld,
Frederick Klauschen,
Michael Bockmayr,
Jochen K. Lennerz,
Carsten Denkert,
Thomas Wolf,
Arne Warth,
Manfred Dietel,
Ioannis Anagnostopoulos,
Wilko Weichert,
Daniel Wittschieber,
and Albrecht Stenzinger
|
| 570-583 |
