Targeting PINK1 and MQC in brain tumors
Targeting PINK1 and MQC in brain tumors |
|
https://doi.org/10.18632/oncotarget.1980
Kyu-Sun Lee,
and Bingwei Lu
|
| 2864-2865 |
HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development
HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development |
|
https://doi.org/10.18632/oncotarget.2003
Stephen P. Hack,
Jean-Marie Bruey,
and Hartmut Koeppen
|
| 2866-2880 |
GSK-3 as potential target for therapeutic intervention in cancer
GSK-3 as potential target for therapeutic intervention in cancer |
|
https://doi.org/10.18632/oncotarget.2037
James A. McCubrey,
Linda S. Steelman,
Fred E. Bertrand,
Nicole M. Davis,
Melissa Sokolosky,
Steve L. Abrams,
Giuseppe Montalto,
Antonino B. D’Assoro,
Massimo Libra,
Ferdinando Nicoletti,
Roberta Maestro,
Jorg Basecke,
Dariusz Rakus,
Agnieszka Gizak,
Zoya Demidenko,
Lucio Cocco,
Alberto M. Martelli,
and Melchiorre Cervello
|
| 2881-2911 |
A highly recurrent RPS27 5’UTR mutation in melanoma
A highly recurrent RPS27 5’UTR mutation in melanoma |
|
https://doi.org/10.18632/oncotarget.2048
Ken Dutton-Regester,
Jared J. Gartner,
Rafi Emmanuel,
Nouar Qutob,
Michael A. Davies,
Jeffrey E. Gershenwald,
William Robinson,
Steven Robinson,
Steven A. Rosenberg,
Richard A. Scolyer,
Graham J. Mann,
John F. Thompson,
Nicholas K. Hayward,
and Yardena Samuels
|
| 2912-2917 |
microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta
microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta |
|
https://doi.org/10.18632/oncotarget.1577
Lidia Ruiz-Llorente,
Soraya Ardila-González,
Luisa F Fanjul,
Olaia Martínez-Iglesias,
and Ana Aranda
|
| 2918-2933 |
Necrosis-targeted combinational theragnostic approach to treat cancer
Necrosis-targeted combinational theragnostic approach to treat cancer |
|
https://doi.org/10.18632/oncotarget.1728
Yun Ji,
Xiaolong Hou,
Cuihua Jiang,
Wei Liu,
Meng Gao,
Yue Li,
Junhun Wang,
Qingqing Wang,
Ziping Sun,
Xiao Jiang,
Nan Yao,
Xiaoning Wang,
Zhijun Fang,
Zhiqi Yin,
Jian Zhang,
and Yicheng Ni
|
| 2934-2946 |
Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation
Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation |
|
https://doi.org/10.18632/oncotarget.1615
Hua Yang,
Harshani Lawrence,
Aslamuzzaman Kazi,
Harsukh Gevariya,
Ronil Patel,
Yunting Luo,
Uwe Rix,
Ernst Schonbrunn,
Nicholas J. Lawrence,
and Said M Sebti
|
| 2947-2961 |
Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production
Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production |
|
https://doi.org/10.18632/oncotarget.1561
Yosuke Togashi,
Tokuzo Arao,
Hiroki Kato,
Kazuko Matsumoto,
Masato Terashima,
Hidetoshi Hayashi,
Marco A. de Velasco,
Yoshihiko Fujita,
Hideharu Kimura,
Takushi Yasuda,
Hitoshi Shiozaki,
and Kazuto Nishio
|
| 2962-2973 |
MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression
MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression |
|
https://doi.org/10.18632/oncotarget.1614
Lekun Fang,
Haoran Li,
Lei Wang,
Jun Hu,
Tianru Jin,
Jianping Wang,
and Burton B. Yang
|
| 2974-2987 |
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis |
|
https://doi.org/10.18632/oncotarget.1634
Fabian Treude,
Ferdinand Kappes,
Dirk Fahrenkamp,
Gerhard Müller-Newen,
Federico Dajas-Bailador,
Oliver H. Krämer,
Bernhard Lüscher,
and Jörg Hartkamp
|
| 2988-2998 |
WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling
WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling |
|
https://doi.org/10.18632/oncotarget.1626
Steffen Ormanns,
Jens Neumann,
David Horst,
Thomas Kirchner,
and Andreas Jung
|
| 2999-3011 |
Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing
Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing |
|
https://doi.org/10.18632/oncotarget.1687
Filip Janku,
Ahmed O. Kaseb,
Apostolia M. Tsimberidou,
Robert A. Wolff,
and Razelle Kurzrock
|
| 3012-3022 |
Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors
Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors |
|
https://doi.org/10.18632/oncotarget.1814
Albert A. Antolín,
and Jordi Mestres
|
| 3023-3028 |
Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway
Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway |
|
https://doi.org/10.18632/oncotarget.1799
Jennifer J. Wheler,
Stacy L. Moulder,
Aung Naing,
Filip Janku,
Sarina A. Piha-Paul,
Gerald S. Falchook,
Ralph Zinner,
Apostolia M. Tsimberidou,
Siqing Fu,
David S. Hong,
Johnique T. Atkins,
Roman Yelensky,
Philip J. Stephens,
and Razelle Kurzrock
|
| 3029-3038 |
Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity
Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity |
|
https://doi.org/10.18632/oncotarget.1747
Lavinia Raimondi,
Nicola Amodio,
Teresa Di Martino,
Emanuela Altomare,
Marzia Leotta,
Daniele Caracciolo,
Annamaria Gullà,
Antonino Neri,
Simona Taverna,
Riccardo Alessandro,
Antonio Giordano,
Pierosandro Tagliaferri,
and Pierfrancesco Tassone
|
| 3039-3054 |
17β-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells
17β-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells |
|
https://doi.org/10.18632/oncotarget.1824
Paul K. Wright,
Sarah Bowen Jones,
Nicholas Ardern,
Rebecca Ward,
Robert B. Clarke,
Federica Sotgia,
Michael P. Lisanti,
Goran Landberg,
and Rebecca Lamb
|
| 3055-3065 |
Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis
Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis |
|
https://doi.org/10.18632/oncotarget.1827
Qing Bo Huang,
Xin Ma,
Hong Zhao Li,
Qing Ai,
Shang Wen Liu,
Yu Zhang,
Yu Gao,
Yang Fan,
Dong Ni,
Bao Jun Wang,
and Xu Zhang
|
| 3066-3075 |
Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients |
|
https://doi.org/10.18632/oncotarget.1832
Harriet Wikman,
Laura Westphal,
Felicitas Schmid,
Sirkku Pollari,
Jolanthe Kropidlowski,
Bettina Sielaff-Frimpong,
Markus Glatzel,
Jakob Matschke,
Manfred Westphal,
Kristiina Iljin,
Heini Huhtala,
Luigi Terracciano,
Anne Kallioniemi,
Guido Sauter,
Volkmar Müller,
Isabell Witzel,
Katrin Lamszus,
Dirk Kemming,
and Klaus Pantel
|
| 3076-3087 |
Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma
Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma |
|
https://doi.org/10.18632/oncotarget.1816
Kaishun Hu,
Dan Liao,
Wenjing Wu,
An-Jia Han,
Hui-Juan Shi,
Fen Wang,
Xin Wang,
Li Zhong,
Tingmei Duan,
Yuanzhong Wu,
Jingying Cao,
Jianjun Tang,
Yi Sang,
Li Wang,
Xiaobin Lv,
Shuangbing Xu,
Ru-Hua Zhang,
Wu-Guo Deng,
Sheng-Ping Li,
Yi-Xin Zeng,
and Tiebang Kang
|
| 3088-3100 |
Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity
Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity |
|
https://doi.org/10.18632/oncotarget.1820
Maxim A. Shevtsov,
Elena Y. Komarova,
Darya A. Meshalkina,
Natalia V. Bychkova,
Nikolai D. Aksenov,
Sergey V. Abkin,
Boris A. Margulis,
and Irina V. Guzhova
|
| 3101-3114 |
The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma
The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma |
|
https://doi.org/10.18632/oncotarget.1821
Ken Maes,
Eva De Smedt,
Miguel Lemaire,
Hendrik De Raeve,
Eline Menu,
Els Van Valckenborgh,
Steve McClue,
Karin Vanderkerken,
and Elke De Bruyne
|
| 3115-3129 |
Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis
Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis |
|
https://doi.org/10.18632/oncotarget.1861
Mourad Sanhaji,
Andreas Ritter,
Hannah R. Belsham,
Claire T. Friel,
Susanne Roth,
Frank Louwen,
and Juping Yuan
|
| 3130-3144 |
Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer
Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer |
|
https://doi.org/10.18632/oncotarget.1865
Fares Al-Ejeh,
Mariska Miranda,
Wei Shi,
Peter T. Simpson,
Sarah Song,
Ana Cristina Vargas,
Jodi M. Saunus,
Chanel E. Smart,
Mythily Mariasegaram,
Adrian P. Wiegmans,
Georgia Chenevix-Trench,
Sunil R. Lakhani,
and Kum Kum Khanna
|
| 3145-3158 |
Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation
Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation |
|
https://doi.org/10.18632/oncotarget.1868
Tom Groot Kormelink,
Desmond G. Powe,
Sylvia A. Kuijpers,
Abulikemu Abudukelimu,
Marcel H.A.M. Fens,
Ebel H.E. Pieters,
Willemiek W. Kassing-van der Ven,
Hany O. Habashy,
Ian O. Ellis,
Bart R. Blokhuis,
Marco Thio,
Wim E. Hennink,
Gert Storm,
Frank A. Redegeld,
and Raymond M. Schiffelers
|
| 3159-3167 |
Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL)
Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL) |
|
https://doi.org/10.18632/oncotarget.1873
Marie Loosveld,
Rémy Castellano,
Stéphanie Gon,
Armelle Goubard,
Thomas Crouzet,
Laurent Pouyet,
Thomas Prebet,
Norbert Vey,
Bertrand Nadel,
Yves Collette,
and Dominique Payet-Bornet
|
| 3168-3172 |
Methylation of CpG sites in RNF180 DNA promoter prediction poor survival of gastric cancer
Methylation of CpG sites in RNF180 DNA promoter prediction poor survival of gastric cancer |
|
https://doi.org/10.18632/oncotarget.1888
Jingyu Deng,
Han Liang,
Guoguang Ying,
Rupeng Zhang,
Baogui Wang,
Jun Yu,
Daiming Fan,
and Xishan Hao
|
| 3173-3183 |
SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells
SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells |
|
https://doi.org/10.18632/oncotarget.1899
Sylvia Müller,
Yuan Chen,
Torsten Ginter,
Claudia Schäfer,
Marc Buchwald,
M. Lienhard Schmitz,
Jana Klitzsch,
Alexander Schütz,
Andrea Haitel,
Katharina Schmid,
Richard Moriggl,
Lukas Kenner,
Karlheinz Friedrich,
Claude Haan,
Iver Petersen,
Thorsten Heinzel,
and Oliver H. Krämer
|
| 3184-3196 |
Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs
Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs |
|
https://doi.org/10.18632/oncotarget.1900
Zijian Li,
Hae Ryon Park,
Zhi Shi,
Zenggang Li,
Cau Dinh Pham,
Yuhong Du,
Fadlo R. Khuri,
Youyi Zhang,
Qide Han,
and Haian Fu
|
| 3197-3209 |
Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients.
Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients. |
|
https://doi.org/10.18632/oncotarget.1907
Pinaki Bose,
Satbir S. Thakur,
Nigel T. Brockton,
Alexander C. Klimowicz,
Elizabeth Kornaga,
Steven C. Nakoneshny,
Karl T. Riabowol,
and Joseph C. Dort
|
| 3210-3219 |
RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis
RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis |
|
https://doi.org/10.18632/oncotarget.1908
Mathias Dahlmann,
Anna Okhrimenko,
Patrick Marcinkowski,
Marc Osterland,
Pia Herrmann,
Janice Smith,
Claus W. Heizmann,
Peter M. Schlag,
and Ulrike Stein
|
| 3220-3233 |
HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels
HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels |
|
https://doi.org/10.18632/oncotarget.1914
Francesca Puca,
Marianna Colamaio,
Antonella Federico,
Marica Gemei,
Nadia Tosti,
André Uchimura Bastos,
Luigi Del Vecchio,
Salvatore Pece,
Sabrina Battista,
and Alfredo Fusco
|
| 3234-3245 |
The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer
The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer |
|
https://doi.org/10.18632/oncotarget.1922
Gonzalo Sequeira,
Silvia I. Vanzulli,
Paola Rojas,
Caroline Lamb,
Lucas Colombo,
María May,
Alfredo Molinolo,
and Claudia Lanari
|
| 3246-3260 |
Rad51 supports triple negative breast cancer metastasis.
Rad51 supports triple negative breast cancer metastasis. |
|
https://doi.org/10.18632/oncotarget.1923
Adrian P. Wiegmans,
Fares Al-Ejeh,
Nicole Chee,
Pei-Yi Yap,
Julia J. Gorski,
Leonard Da Silva,
Emma Bolderson,
Georgia Chenevix-Trench,
Robin Anderson,
Peter T. Simpson,
Sunil R. Lakhani,
and Kum Kum Khanna
|
| 3261-3272 |
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy |
|
https://doi.org/10.18632/oncotarget.1926
Rachel Abbotts,
Rosalyn Jewell,
Jérémie Nsengimana,
David J. Maloney,
Anton Simeonov,
Claire Seedhouse,
Faye Elliott,
Jon Laye,
Christy Walker,
Ajit Jadhav,
Anna Grabowska,
Graham Ball,
Poulam M. Patel,
Julia Newton-Bishop,
David M. Wilson III,
and Srinivasan Madhusudan
|
| 3273-3286 |
Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range
Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range |
|
https://doi.org/10.18632/oncotarget.1935
Brook T. Chernet,
and Michael Levin
|
| 3287-3306 |
Negative regulation of DAB2IP by Akt and SCFFbw7 pathways
Negative regulation of DAB2IP by Akt and SCFFbw7 pathways |
|
https://doi.org/10.18632/oncotarget.1939
Xiangpeng Dai,
Brian J. North,
and Hiroyuki Inuzuka
|
| 3307-3315 |
The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors
The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors |
|
https://doi.org/10.18632/oncotarget.1945
Bhaskar Kahali,
Jinlong Yu,
Stefanie B. Marquez,
Kenneth W. Thompson,
Shermi Y. Liang,
Li Lu,
and David Reisman
|
| 3316-3332 |
HDAC 1/4-mediated silencing of microRNA-200b promotes chemoresistance in human lung adenocarcinoma cells
HDAC 1/4-mediated silencing of microRNA-200b promotes chemoresistance in human lung adenocarcinoma cells |
|
https://doi.org/10.18632/oncotarget.1948
Dong-Qin Chen,
Ban-Zhou Pan,
Jia-Yuan Huang,
Kai Zhang,
Shi-Yun Cui,
Wei De,
Rui Wang,
and Long-Bang Chen
|
| 3333-3349 |
Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine
Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine |
|
https://doi.org/10.18632/oncotarget.1949
Masamichi Hayashi,
Heike Bernert,
Luciane Tsukamoto Kagohara,
Leonel Maldonado,
Mariana Brait,
Mark Schoenberg,
Trinity Bivalacqua,
George J. Netto,
Wayne Koch,
David Sidransky,
and Mohammad O. Hoque
|
| 3350-3361 |
Combination of PIM and JAK2 inhibitors synergistically suppresses cell proliferation and overcomes drug resistance of myeloproliferative neoplasms
Combination of PIM and JAK2 inhibitors synergistically suppresses cell proliferation and overcomes drug resistance of myeloproliferative neoplasms |
|
https://doi.org/10.18632/oncotarget.1951
Shih-Min A. Huang,
Anlai Wang,
Rita Greco,
Zhifang Li,
Claude Barberis,
Michel Tabart,
Vinod Patel,
Laurent Schio,
Raelene Hurley,
Hong Cheng,
Christoph Lengauer,
Jack Pollard,
James Watters,
Carlos Garcia-Echeverria,
Dmitri Wiederschain,
Francisco Adrian,
and JingXin Zhang
|
| 3362-3374 |
Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers
Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers |
|
https://doi.org/10.18632/oncotarget.1952
Chong-kui Sun,
Fan Zhang,
Tao Xiang,
Qianming Chen,
Tej K. Pandita,
Yuping Huang,
Mickey C.T. Hu,
and Qin Yang
|
| 3375-3385 |
Up-regulation of neogenin-1 increases cell proliferation and motility in gastric cancer
Up-regulation of neogenin-1 increases cell proliferation and motility in gastric cancer |
|
https://doi.org/10.18632/oncotarget.1960
Seok-Jun Kim,
Yuan-Guo Wang,
Hyun-Woo Lee,
Hyeok Gu Kang,
Sun-Hyuk La,
Il Ju Choi,
Tatsuro Irimura,
Jae Y. Ro,
Robert S. Bresalier,
and Kyung-Hee Chun
|
| 3386-3398 |
Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma
Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma |
|
https://doi.org/10.18632/oncotarget.1975
Chul-Kee Park,
Se-Hoon Lee,
Ji Young Kim,
Ja Eun Kim,
Tae Min Kim,
Soon-Tae Lee,
Seung Hong Choi,
Sung-Hye Park,
and Il Han Kim
|
| 3399-3407 |
ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents
ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents |
|
https://doi.org/10.18632/oncotarget.1982
Marion Le Grand,
Amandine Rovini,
Veronique Bourgarel-Rey,
Stephane Honore,
Sonia Bastonero,
Diane Braguer,
and Manon Carre
|
| 3408-3423 |
