Oncotarget

Volume 3, Issue 5

May 2012

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About The Cover

Representative images of immunohistochemical staining for Extracellular Sulfatase Sulf-2 (SULF2) in pediatric Glioblastoma (GBM). See Phillips et al.

Table of Contents

Editorial Comments

Targeting Protein-Tyrosine Phosphatases in Breast Cancer

Targeting Protein-Tyrosine Phosphatases in Breast Cancer

https://doi.org/10.18632/oncotarget.496

Nicola Aceto,  and Mohamed Bentires-Alj
514-515
Abstract  |  PDF  |  HTML  |  How to cite

Voltage-dependent K+ channels as oncotargets in malignant gliomas

Voltage-dependent K+ channels as oncotargets in malignant gliomas

https://doi.org/10.18632/oncotarget.514

Florence Lefranc, Henri-Benjamin Pouleau, Michal Rynkowski,  and Olivier De Witte
516-517
Abstract  |  PDF  |  HTML  |  How to cite

Brief Reports

A novel co-operative mechanism linking TGFβ and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells

A novel co-operative mechanism linking TGFβ and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells

https://doi.org/10.18632/oncotarget.500

Andrew Chantry, Paul G Smith,  and Hideo Tanaka
518-524
Abstract  |  PDF  |  HTML  |  How to cite

Research Papers

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells

https://doi.org/10.18632/oncotarget.491

Elisabeth J. Walsby, Laurence Pearce, Alan K. Burnett, Chris Fegan,  and Chris Pepper
525-534
Abstract  |  PDF  |  HTML  |  How to cite

A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma.

A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma.

https://doi.org/10.18632/oncotarget.498

Francesco Sottile, Ilaria Gnemmi, Sandra Cantilena, Walter C. D'Acunto,  and Arturo Sala
535-545
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase.

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase.

https://doi.org/10.18632/oncotarget.503

Hongdo Do,  and Alexander Dobrovic
546-558
Abstract  |  PDF  |  HTML  |  How to cite

Research Perspectives

Solid Tumor Differentiation Therapy – Is It Possible?

Solid Tumor Differentiation Therapy – Is It Possible?

https://doi.org/10.18632/oncotarget.512

Filemon Dela cruz,  and Igor Matushansky
559-567
Abstract  |  PDF  |  HTML  |  How to cite

Novel Therapeutic Targets in the Brain Tumor Microenvironment

Novel Therapeutic Targets in the Brain Tumor Microenvironment

https://doi.org/10.18632/oncotarget.526

Joanna J. Phillips
568-575
Abstract  |  PDF  |  HTML  |  How to cite

FLT3 in lineage specification and plasticity

FLT3 in lineage specification and plasticity

https://doi.org/10.18632/oncotarget.499

Sarah Greenblatt,  and Donald Small
576-580
Abstract  |  PDF  |  HTML  |  How to cite

Cell-based high-throughput screens for the discovery of chemotherapeutic agents

Cell-based high-throughput screens for the discovery of chemotherapeutic agents

https://doi.org/10.18632/oncotarget.513

Jennifer T Fox,  and Kyungiae Myung
581-585
Abstract  |  PDF  |  HTML  |  How to cite

Methodological Reports

Mantle cell lymphoma-like lymphomas in c-myc-3’RR/p53+/- mice and c-myc-3’RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin

Mantle cell lymphoma-like lymphomas in c-myc-3’RR/p53+/- mice and c-myc-3’RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin

https://doi.org/10.18632/oncotarget.474

Pauline Rouaud, Rémi Fiancette, Christelle Vincent-Fabert, Virginie Magnone, Michel Cogné, Pierre Dubus,  and Yves Denizot
586-593
Abstract  |  PDF  |  HTML  |  How to cite


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